Myfootshop.com foot and ankle blog

February 26, 2009

Uloric soon to hit the market as a new medication to treat gout.

Filed under: Foot and ankle conditions — Tags: , , , — Jeffrey Oster, DPM @ 2:48 am

Takeda Pharmaceuticals of Osaka, Japan won FDA approval yesterday to market a new uricosuric agent in the US market for the treatment of gout.  The drug will be marketed as Uloric (febuxostat) and will be marketed as an alternative to allopurinal.

I’ve prescribed allopurinal for years with no ill effects.  My question is this; what are the benefits of Uloric?  As a new patented medication, Uloric is sure to cost much more than generic allopurinal.  I think the jury is still out.

Jeffrey A. Oster, DPM
Medical Director
Myfootshop.com

February 18, 2009

Charcot Arthropathy – what’s the standard of care?

Charcot arthropathy is commonly associated with diabetes.  But diabetes only represents one of many ways in which the normal sensation to the foot is disrupted.  This disruption of normal sensation is called peripheral neuropathy (PN).  Other common contributing factors to PN include lumbar radiculopathy (lumbar pain), lumbar surgery, alcohol abuse or chemotherapy.  PN diminishes the ability to feel pain.  As a result of this loss of sensation, patients undergo micro-fractures that propagates within the the bone adjacent to the joints of the midfoot or ankle.

What’s the standard of care for Charcot arthropathy?  In newly diagnosed cases, the standard of care is prompt off-loading of the foot.  The diagnosis of Charcot arthropathy does require a high degree of suspicion on the part of the physician and is an often overlooked diagnosis.  

But what about long term management of Charcot arthropathy?  That’s where the standard of care is poorly defined.  Will reconstructive surgery help?  When is amputation indicated?  

I think we have a lot to learn about the long term management of Charcot arthropathy.  But most importantly, the bottom line is to prevent the onset of PN in the first place. 

Jeffrey Oster, DPM
Medical Director
Myfootshop.com

February 13, 2009

Is it possible to differentiate sesamoiditis from a sesamoid fracture or AVN?

Filed under: Foot and ankle surgery, Foot and ankle trauma — Jeffrey Oster, DPM @ 1:55 am

In the early stages of a sesamoid injury, it can be difficult to differentiate between these conditions.  Remember, when I say injury, it’s not necessarily a fall or abrupt injury that can lead to sesamoid injuries.  Many cases are simply due to foot structure that makes you predisposed to sesamoid injury.

Join us in this discussion on sesamoid injuries in The Foot Talk Forum for more information.  You can also find more information in our pages on sesamoiditis and sesamoid injuries.

Jeffrey A. Oster, DPM
Medical Director
Myfootshop.com

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